- Best seller
- Refillable
Moisturizer
Barrier Repair Cream
Ceramides, cholesterol and fatty acids in the 3:1:1 ratio your barrier already uses
From $18

Barrier-first skincare, made in short formulas
Ceramides, cholesterol and fatty acids in the 3:1:1 ratio skin builds its own barrier with. Actives dosed at strengths you can read on the label. Nothing fragranced, anywhere in the catalog.
Best sellers
Most of what we ship is a repeat order. These are the formulas behind that: a cream, its refill, a cleanser that does not strip and a mineral sunscreen that does not pill.
See all best sellersMoisturizer
Ceramides, cholesterol and fatty acids in the 3:1:1 ratio your barrier already uses
From $18
Refill
The same Barrier Repair Cream, for the jar you already own
From $36
Shop by line
A routine is easier to build when every product says what it is for. Each line names its actives, its percentages and its pH on the carton.
Barrier
Repair first, everything else after
Shop Barrier
Acids
Resurfacing on a schedule, never on impulse
Shop Acids
Cleanse
Take the day off without taking the barrier with it
Shop Cleanse
Actives
One active, one job, one honest percentage
Shop Actives
Sun
The last step, and the one that decides the others
Shop Sun
Sets
A routine, not a discount bundle
Shop Sets
What we believe
The outer layer of skin is held together by three lipids: ceramides, cholesterol and free fatty acids. When that layer is intact, skin holds water and shrugs off most of what touches it. When it is worn down, by over-cleansing, by too many acids, by a dry winter, everything stings and nothing seems to work.
So we start there. Every Seravane routine begins with a cleanser mild enough to forget about and a moisturizer built on the same three lipids, in the 3:1:1 ratio skin already uses. Actives come second, one at a time, at a percentage printed on the front of the bottle.
We would rather tell you what a formula cannot do than sell you a promise. An eye balm does not erase dark circles. A 10% niacinamide is not better than a 6% one. A label you can read without a glossary is the least a skincare brand owes you.
Juliette Marsden and Tobias Renwick, co-founders
Read our story
Clinical results
We commission instrumental and consumer-use studies on our own formulas and publish the design, the sample size and the results, including the ones that are only modest.
Read the full results23%
less water lost through the skin after 4 weeks of Barrier Repair Cream
Mean reduction in transepidermal water loss, instrumental study, 32 adults, twice-daily use.
93%
said their skin felt less tight after washing
Consumer-use study of Barrier Repair Cream, 108 participants, 4 weeks, self-assessed.
3:1:1
ceramides to cholesterol to fatty acids, printed on the carton
The molar ratio of the lipid blend in the Barrier Repair Cream and its refill.
82%
less packaging by weight in a refill pouch than in a new jar
Pouch weight compared with the 50 ml glass jar, lid and carton.

Routine Builder
Tell us about your skin and what you already use. The Routine Builder returns three to five products and the order of steps, with the reason for each one written next to it. It takes about a minute, and no email is needed to see the result.

Refill Program
The Barrier Repair Cream jar is glass with a metal lid, and it is built to be refilled. The pouch holds the same 50 ml of the same formula, costs 25% less per ml and ships flat enough to fit a mailbox.
Sets
Each set ships with a printed order of use. One is the routine for a barrier that needs rebuilding, the other is the three steps that do most of the work.
Shop setsSet
Cleanser, serum and cream, full size, in the order they are meant to be used
$118
Set
Cleanser, moisturizer and sunscreen: the three steps that do most of the work
$86
From verified reviews
I had stripped my face with a foaming cleanser and three different acids. Two weeks of only the cleanser and this cream and my cheeks stopped stinging when I washed them. I am on my fourth refill.
Priya S.
Barrier Repair Cream
The first mineral sunscreen I have used in the Medium–Deep tint that does not turn gray on me by lunchtime. It sits under foundation without rolling into little balls.
Danielle O.
Fluid Mineral SPF 46
I like that the carton tells me the percentage and the pH and then tells me to use it twice a week, not every night. It is the first acid I have not overdone.
Marcus T.
10% Mandelic Resurface
It does what it says and it says very little. No scent, no tight feeling, takes my sunscreen off in one wash. I bought the 300 ml and stopped thinking about cleanser.
Hannah W.
Gel-to-Milk Cleanser
The pouch is a little fiddly the first time, I will be honest. But it is the same cream for twelve dollars less and one jar has now lasted me a year and a half.
Elena R.
Refill Pouch - Barrier Cream
A 10% niacinamide made my face flush. This one at 6% never has, and my forehead is noticeably less shiny by the afternoon.
Jordan K.
Niacinamide 6% Fluid
Journal
Notes from our formulation team on how skin works and how to use what we make.
Visit the Journal